Slow Cooked, edition 2. One long read a month.
"It's all in your head." The most harmful half-truth in medicine.
The gut has a nervous system of its own, in constant conversation with the brain. Once you know that, the sentence stops being a dismissal and becomes the beginning of the explanation.
Dr Parisah HussainChief Medical Officer, Suna Health. 5 min read.
People with IBS are often left with the sense that normal test results mean nothing is wrong with them. The science says something quite different. IBS is now formally classed as a disorder of the conversation between two nervous systems, which is why what you feel is real, why a scan cannot photograph it, and why the things that help work at both ends of that circuit.
The sentence
There is a moment I have watched from both sides of the desk. The tests have come back. The doctor says the words "all normal", and means them kindly. And somewhere between "normal" and the end of the appointment, a sentence lands that may never have been said out loud: it's all in your head. You are imagining it. Nothing is wrong with you.
If you live with irritable bowel syndrome, or IBS, you may know that moment personally. Perhaps you left it feeling relieved for an afternoon and dismissed for a decade.
I want to take that sentence apart, keep the half of it that is true, and throw away the half that has done so much harm. Because the strange truth about IBS is this: it does involve your head, profoundly, and that is precisely why what you feel is real.
Real, common, and taken less seriously than it should be
IBS is one of the most common things a doctor sees. It affects roughly 5 to 10% of people worldwide (Mayer 2023), most often women, and it does not shorten life. But it changes life: research shows it affects day-to-day quality of life as much as gut conditions everyone accepts as serious (BSG, Vasant 2021).
And yet the stigma runs the other way. A review in The Lancet Gastroenterology and Hepatology found the stigma around IBS is common among the public, co-workers and even health professionals, and in comparative studies it runs higher for IBS than for inflammatory bowel disease (Hearn 2020). Decades of research says people with IBS often feel labelled as neurotic, and let down (Dixon-Woods 2000). Told, in other words, that it is all in their head.
What the sentence gets right
Now the interesting part. The brain really is central to IBS, and science has stopped calling it a "functional" disorder, a word people rightly heard as "we found nothing". Its formal name today is a disorder of gut-brain interaction (Rome IV, Drossman 2016): a condition of the conversation between two nervous systems.
Your gut has a nervous system of its own, hundreds of millions of neurons woven through its walls (Fleming 2020). It runs digestion largely on autopilot, but it is in constant two-way conversation with your brain, through the vagus nerve and the same wiring that runs your fight-or-flight response.
That conversation is where IBS lives. When life tips you toward fight-or-flight, the balance of signals to your gut shifts, changing how it moves, how sensitive it is, even how its lining behaves (BSG, Vasant 2021). This is why a stressful week can genuinely change your bathroom patterns. Not metaphorically. Mechanically. The same brain that gets you through a difficult conversation is sending instructions to your bowel while it does it.
Then there is the volume dial. In many people with IBS, the gut's ordinary signals, the stretching and squeezing everyone produces all day, arrive at the brain amplified, and land as pain (BSG, Vasant 2021). The signal processing is different. And pain made in the nervous system is what all pain is, from a stubbed toe to a stormy gut.
So yes. IBS is, in a very specific sense, "in your head", and in your gut's own second brain, and in the conversation between them. What it is not, anywhere in the science, is imaginary.
Why the scans come back "normal"
Many people experience the road to IBS as a hunt for the thing the cameras will finally find. But IBS is a pattern doctors can recognise in its own right, from what you feel and how it behaves over time, alongside a small set of checks to rule out look-alikes (NICE CG61). What it is not is an endless process of elimination.
Here is the reframe worth keeping: IBS lives in the signalling between brain and gut, and a camera cannot photograph a conversation. A "normal" scan is not medicine failing to find your problem. It is the pattern confirming itself, and it is the moment the real work, calming the conversation, can begin.
What helps
The honest headline: there is no switch that turns the syndrome off. But the conversation between brain and gut can genuinely be turned down, and the things that help map neatly onto the circuit itself.
At the gut end, food patterns matter: the right kinds of fibre genuinely help many people, while some everyday foods can turn the volume up, and a structured short-term reset of fermentable foods, ideally guided by a dietitian, has good evidence behind it (BSG, Vasant 2021).
At the brain end, the practices that work are not "just relaxing": IBS-specific talking therapies and gut-directed hypnotherapy both carry strong recommendations in the UK national guideline, precisely because they reach the gut through the brain's half of the conversation (Black 2020; BSG, Vasant 2021). We'll take a proper look at gut-directed hypnotherapy in a coming article.
And there are also medicine options, from soothing an over-eager bowel to quieting oversensitive gut nerves. Which of them fits you, if any, is a conversation for you and your own doctor, and a good one to have armed with everything above.
Reclaiming the sentence
The sentence was half right all along. IBS does involve your head. But "it's all in your head" should never have meant "what you feel is fake". It should have meant something closer to this: your brain and your gut are talking over each other, the volume is up, and that circuit, not your character, is what needs looking after.
The research on what people want is not complicated: to be believed, and to be given an explanation that makes sense of their own body (Dixon-Woods 2000). If you live with IBS, that is what you are owed. What you feel is real. The mechanism is real. And "normal tests" were never a verdict on you. They were the pattern, recognising itself.
Sources
- Irritable bowel syndrome in adults: diagnosis and management (NICE CG61)
- British Society of Gastroenterology guidelines on the management of irritable bowel syndrome (Vasant et al., Gut, 2021)
- Rome IV, functional GI disorders: disorders of gut-brain interaction (Drossman & Hasler, Gastroenterology, 2016)
- The neurobiology of irritable bowel syndrome (Mayer et al., Molecular Psychiatry, 2023)
- The enteric nervous system and its emerging role as a therapeutic target (Fleming et al., Gastroenterology Research and Practice, 2020)
- Stigma and irritable bowel syndrome (Hearn, Whorwell & Vasant, Lancet Gastroenterology & Hepatology, 2020)
- Involving patients in decisions: what people with IBS say they want (Dixon-Woods & Critchley, Family Practice, 2000)
- Efficacy of psychological therapies for irritable bowel syndrome (Black et al., Gut, 2020)